Interval mapping of growth quantitative trait loci in Japanese Black beef cattle using microsatellite DNA markers and half-sib regression analysis

نویسندگان

  • Aduli Enoch Othniel Malau-Aduli
  • Aduli Enoch Othniel MALAU-ADULI
  • Tomomi NIIBAYASHI
  • Takatoshi KOJIMA
  • Kazunaga OSHIMA
  • Yasushi MIZOGUCHI
  • Masanori KOMATSU
چکیده

A confirmatory scan for the regions of bovine chromosome 1 segregating the quantitative trait loci (QTL) influencing birthweight, weaning weight, yearling weight, and preweaning and postweaning average daily gains was performed by genotyping half-sib progeny of four Japanese Black sires using microsatellite DNA markers. Data were analyzed by generating an F -statistic every 1 cM on a linkage map by the regression of phenotype on the probabilities of inheriting an allele from the sire after adjusting for the fixed effects of sire, sex, parity and season of birth as well as age as a covariate. Permutation tests at chromosome-wide significance thresholds were carried out over 10 000 iterations. A significant QTL for birthweight at 114 cM was detected in the sire 2 family. This identification of a birthweight QTL in Japanese Black cattle may be useful for the implementation of marker-assisted selection.

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تاریخ انتشار 2005